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Skeletal formula of allithiamine
Ball-and-stick model of the allithiamine molecule
Clinical data
ATC code
  • None
CAS Number
PubChem CID
Chemical and physical data
Molar mass354.49 g/mol g·mol−1
3D model (JSmol)
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Allithiamine (thiamine allyl disulfide or TAD) is a lipid-soluble form of vitamin B1 which was discovered in garlic (Allium sativum) in the 1950s along with its homolog prosultiamine.[1] They were both investigated for their ability to treat Wernicke–Korsakoff syndrome and beriberi better than thiamine.[2]

See also[edit]


  1. ^ Fujiwara, Motonori; Watanabe, Hiroshi; Matsui, Kiyoo (1954). ""Allithiamine" A Newly Found Derivative of Vitamin B1". The Journal of Biochemistry. 41: 29. doi:10.1093/oxfordjournals.jbchem.a126421.
  2. ^ Rogers, Edward F (1962). "Thiamine Antagonists". Annals of the New York Academy of Sciences. 98 (2): 412. Bibcode:1962NYASA..98..412R. doi:10.1111/j.1749-6632.1962.tb30563.x.